ARA290 10mg
$60.00
ARA-290 (also known as Cibinetide) is an investigational 11-amino-acid synthetic peptide derived from erythropoietin (EPO). Engineered to selectively target the body's Innate Repair Receptor (IRR), it aims to reduce inflammation, promote tissue repair, and relieve neuropathic pain without stimulating red blood cell production.
Key Mechanisms & Research
- Innate Repair Receptor (IRR) Activation: Unlike full-length EPO, ARA-290 specifically binds to the IRR, which is expressed on stressed or injured tissues, triggering protective and anti-inflammatory pathways.
- Neuropathic Pain & Inflammation: Research indicates it may reduce pain by suppressing spinal microglial responses and acting as an antagonist to the TRPV1 pain receptor.
- Tissue Repair: Studies have observed ARA-290 helping to regenerate small nerve fibers (e.g., in the cornea and skin) and improving metabolic control and lipid profiles in diabetes models.